Totani M., Kawano T., Shigenobu Y., Kadokawa J.I. . Efficient Benzylation of Chitin in Ionic Liquids . New Journal of Chemistry49 ( 27 ) 11584 -2025 · 担当区分： 筆頭著者 記述言語： 日本語 掲載種別： 研究論文（学術雑誌） 出版者・発行元： New Journal of Chemistry In this study, an efficient benzylation of chitin using benzyl bromide in the presence of LiOH in ionic liquids was developed. Addition of amine bases, such as tributylamine, was found to promote the reaction and yield benzyl chitins with high degrees of substitution. Benzyl tributylammonium bromide, produced in situ, was shown to capably act as an effective phase-transfer catalyst. DOI： 10.1039/d5nj01789k Scopus researchmap
Miyahara Y., Takagagki T., Totani M., Kadokawa J.i. . Glucan Phosphorylase‐Catalyzed Enzymatic Synthesis of a New Unnatural Heteroaminopolysaccharide, Glucosamino‐2‐deoxyglucan, and Its N</2025 · 記述言語： 日本語 掲載種別： 研究論文（学術雑誌） 出版者・発行元： Macromolecular Chemistry and Physics Based on the fact that the enzymatic approach has been identified as a powerful tool to prepare polysaccharides with well-defined structure, this study investigates the enzymatic synthesis of a new unnatural heteroaminopolysaccharide, that is, α((Formula presented.))-linked glucosamino-2-deoxyglucan. The desired heteroaminopolysaccharide is obtained by thermostable glucan phosphorylase (from Aquifex aeolicus VF5)-catalyzed enzymatic copolymerization of α-d-glucosamine 1-phosphate/d-glucal as comonomers from maltotriose as a primer in 0.10 m ammonia buffer containing MgCl2 at 40 °C. The MALDI-TOF MS and 1H NMR spectrum of the isolated product fully supported the heteroaminopolysaccharide structure. The effects of comonomer feed ratios and reaction times on unit ratios and degrees of polymerization (molecular weights), respectively, are precisely investigated. As a representative derivatization using reactive amino groups in the produced heteroaminopolysaccharide, its N-benzylation is attempted using benzyl bromide in DMSO. The N-benzylated derivative exhibited pH responsive property, where the polymeric molecules assembled by hydrophobic interaction among benzyl groups under the neutral aqueous condition, whereas the assemblies are dissociated by electrostatic repulsion via protonation on nitrogen atoms under the acidic condition. The result indicates the potential of the present heteroaminopolysaccharide as biomedical materials in the practical application field. DOI： 10.1002/macp.202500052 Scopus researchmap
Aoki N., Yamazaki J., Matsumoto T., Totani M., Shundo A., Tanaka K., Nishino T. . Analyses and control of interphase structures and adhesion properties of epoxy resin/epoxy resin for developme2024 · 記述言語： 日本語 掲載種別： 研究論文（学術雑誌） 出版者・発行元： Composites Part A: Applied Science and Manufacturing In the adhesion of carbon fiber reinforced plastics (CFRP), the boundary regions were composed of only epoxy resins of CFRP matrix and adhesives, and their similar epoxy structures pose significant difficulty in studying the adhesion mechanism. Herein, we focused on structure and properties of laminates of epoxy resin substrates and adhesives with different curing conditions of substrates. We prepared laminates using deuterated epoxy adhesives or fluorinated epoxy adhesives, and their boundary regions were identified through confocal Raman scattering measurements. The regions were distributed into “penetration” and “interphase”. In particular, the penetration phase is a key of the adhesion properties. The penetration behaviors strongly depended on the crosslinking densities of the adherends, suggesting that the penetration regions would be directly impacted by the curing conditions of the substrates and molecular size of epoxy adhesive precursors. Our findings provide insights into novel designs of the reliable adhesion-based manufacturing systems of CFRP. DOI： 10.1016/j.compositesa.2024.108511 Scopus researchmap
