京都大学 · 医学部・医学研究科

研究キーワードdevelopmental neurotoxicology・perinatal hypothyroidism・PFOS exposure・dioxin exposure・cerebellar development・cognitive development・maternal behavior・behavioral toxicology

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• Motor coordination is partially impaired in neonatal mice with moderate hypothyroidism but not with mild hypothyroidismThyroid Science,
• Differential neurotoxic effects of in utero and lactational exposure to hydroxylated polychlorinated biphenyl (OH-PCB 106) on spontaneous locomotor activity and motor coordination in young adult male miceJOURNAL OF TOXICOLOGICAL SCIENCES,
• In utero and postnatal propylthiouracil-induced mild hypothyroidism impairs maternal behavior in miceFrontiers in Endocrinology,
• Differential effects of different time windows of postnatal perfluorooctane sulfonate exposure on cognitive development in mouse hippocampus.The Journal of toxicological sciences,

• 周産期化学物質曝露による脳機能障害の発症機序の解明と障害の予防・抑制法の開発
• 終脳特異的なガングリオシド欠損が脳発達に及ぼす影響の解析

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