東京科学大学 · 医歯学総合研究科 · 教授

研究キーワードviral hepatitis・hepatocellular carcinoma・chronic hepatitis B・hepatitis C prognosis・HBV therapeutics・iPS cell disease models・liver disease modeling

研究分野消化器内科学・内科学一般およびその関連分野・内科系臨床医学・医歯薬学・生物系

ここは公開データのプレビューです。個別の適合理由、連絡角度、保存機能はログイン後に利用できます。

• Tomohiko Taniai, Shu Shimada, Yoshimitsu Akiyama, Megumi Hatano, Koya Yasukawa, Yosuke Igarashi, Shu Tsukihara, Yoshiaki Tanji, Keita Kodera, Kohei Okazaki, Koichiro Haruki, Atsushi Nara, Kohei Yagi, Keiichi Akahoshi, Daisuke Ban, Yasuhiro Asahina, Toru Ikegami, Minoru Tanabe, Shinji Tanaka. Integrative transcriptome profiling elucidates molecular and immunovascular characteristics of macrotrabecular hepatocellular carcinoma. Hepatology. 2025.02; ( PubMed , DOI )2025
• Jun Tsuchiya, Masato Miyoshi, Sei Kakinuma, Fukiko Kawai-Kitahata, Akihide Kamiya, Taro Shimizu, Ayako Sato, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Rion Kamimae, Shun Kaneko, Miyako Murakawa, Sayuri Nitta, Mina Nakagawa, Mamoru Watanabe, Yasuhiro Asahina, Ryuichi Okamoto. Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived Model. Cell Mol Gastroenterol Hepatol. 2025; 19 (2): 101422. ( PubMed , DOI )2025
• Taro Shimizu, Masato Miyoshi, Sei Kakinuma, Jun Tsuchiya, Daisuke Yamane, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Kaho Yamada, Kotomi Shinozaki, Ayako Sato, Shun Kaneko, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Mina Nakagawa, Mamoru Watanabe, Yasuhiro Asahina, Ryuichi Okamoto. Bile acid-FXR signaling facilitates the long-term maintenance of hepatic characteristics in human iPSC-derived organoids. Cell Rep. 2025.05; 44 (5): 115675. ( PubMed , DOI )2025
• Tomohiro Mochida, Masato Miyoshi, Sei Kakinuma, Taro Shimizu, Jun Tsuchiya, Keiya Watakabe, Kento Inada, Shun Kaneko, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Mina Nakagawa, Mamoru Watanabe, Yasuhiro Asahina, Ryuichi Okamoto. Crosstalk via ICAM-1 enhances supportive phenotype of stellate cells and drives hepatocyte proliferation in iPSC-derived hepatic organoids. Stem Cell Reports. 2025.10; 20 (10): 102642. ( PubMed , DOI )2025

• 公式プロフィール
• KAKEN
• CiNii