東京科学大学 · 医歯学総合研究科

研究キーワード腱の発育・細胞老化・RNA結合タンパク質・RNA修飾・肺がんの転移制御・遺伝子編集マウス

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• Lin Liu, Tomoki Chiba, Takahide Matsushima, Maiko Inotsume, Tomomi Kato, Yuichi Hiraoka, Hiroshi Asahara. Gene dosage-dependent roles of Mkx in postnatal tendon development and maintenance revealed by conditional deletion. Dev Biol. 2025.10; 526 15-25. ( PubMed , DOI )2025
• Yuki Yoshioka, Yong Huang, Xiaocen Jin, Kien Xuan Ngo, Tomohiro Kumaki, Meihua Jin, Saori Toyoda, Sumire Takayama, Maiko Inotsume, Kyota Fujita, Hidenori Homma, Toshio Ando, Hikari Tanaka, Hitoshi Okazawa. PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation. EMBO J. 2024.08; ( PubMed , DOI )2024
• Hidenori Homma, Kien Xuan Ngo, Yuki Yoshioka, Hikari Tanaka, Maiko Inotsume, Kyota Fujita, Toshio Ando, Hitoshi Okazawa. PQBP3/NOL7 is an intrinsically disordered protein. Biochem Biophys Res Commun. 2024.07; 736 150453. ( PubMed , DOI )2024
• Maiko Inotsume, Tomoki Chiba, Takahide Matsushima, Ryota Kurimoto, Mitsuyo Nakajima, Tomomi Kato, Kana Shishido, Lin Liu, Koichi Kawakami, Hiroshi Asahara. One-step generation of mice with gene editing by Tol2 transposon-dependent gRNA delivery. FEBS Lett. 2023.03; ( PubMed , DOI )2023

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