東京科学大学 · 総合研究院

研究キーワードmRNA送達システム・自己組織化・ポリプレックス・ナノ粒子・RNA内包タンパク質ケージ・生体材料

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• Nan Qiao, Mao Hori, Mitsuru Naito, Heemin Chang, Satomi Ogura, Mika Suzuki, Tsuyoshi Kimura, Shigeto Fukushima, Hyun Jin Kim, Satoshi Uchida, Kanjiro Miyata. Increasing polycation hydrophobicity in mRNA polyplex vaccines enhances the efficacy of humoral and cellular immunity induction Biomaterials. 2026.01; 324 123515. ( DOI )2026
• Mao Hori, Nan Qiao, Kohki Yamada, Jongmin Yum, Satomi Ogura, Satoshi Uchida, Hyun Jin Kim, Mitsuru Naito, Kanjiro Miyata. Formulation-Driven Control of mRNA Polyplex Physicochemical Properties Enables Spleen-Targeted Systemic Delivery ACS Applied Bio Materials. 2026.03; ( DOI )2026
• Heemin Chang, Fadlina Aulia, Rimpei Kamegawa, Nan Qiao, Mao Hori, Satomi Ogura, Chun Yin Jerry Lau, Naoki Yamada, Kaori Taniwaki, Mitsuru Naito, Hyun Jin Kim, Kanjiro Miyata. Silica-coated polyion complexes for enhanced pulmonary messenger RNA delivery with optimized silica layer stability Journal of Controlled Release. 2025.08;2025
• Dalia Dranseike, Yusuke Ota, Thomas G W Edwardson, Elia A Guzzi, Mao Hori, Zrinka Raguz Nakic, Dhananjay V Deshmukh, Mikail D Levasseur, Kevin Mattli, Christina M Tringides, Jiangtao Zhou, Donald Hilvert, Christin Peters, Mark W Tibbitt. Designed modular protein hydrogels for biofabrication. Acta Biomater. 2024.03; 177 107-117. ( PubMed , DOI )2024

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