東北大学 · 金属材料研究所

研究キーワードcancer stem cells・cholangiocarcinoma・PKM2 metabolism・gastric cancer・pancreatic ductal adenocarcinoma・HOTAIR・circulating microRNAs・semaphorin 3E

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• Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinomaKeiichi Tamai, Mao Nakamura, Masamichi Mizuma, Mai Mochizuki, Misa Yokoyama, Hiroyuki Endo, Kazunori Yamaguchi, Takayuki Nakagawa, Masaaki Shiina, Michiaki Unno, Koji Muramoto, Ikuro Sato, Kennichi Satoh, Kazuo Sugamura, Nobuyuki Tanaka
• Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen speciesMisa Yokoyama, Nobuhiro Tanuma, Rie Shibuya, Takeharu Shiroki, Makoto Abue, Kuniharu Yamamoto, Koh Miura, Kazunori Yamaguchi, Ikuro Sato, Keiichi Tamai, Kennichi Satoh
• Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolismTakeharu Shiroki, Misa Yokoyama, Nobuhiro Tanuma, Ryuhei Maejima, Keiichi Tamai, Kazunori Yamaguchi, Tomoyuki Oikawa, Tetsuya Noguchi, Koh Miura, Tsuneaki Fujiya, Hiroshi Shima, Ikuro Sato, Naoko Murata-Kamiya, Masanori Hatakeyama, Katsunori Iijima, Tooru Shimosegawa, Kennichi Satoh
• Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancerMakoto Abue, Misa Yokoyama, Rie Shibuya, Keiichi Tamai, Kazunori Yamaguchi, Ikuro Sato, Nobuyuki Tanaka, Shin Hamada, Tooru Shimosegawa, Kazuo Sugamura, Kennichi Satoh

• フュージョンエネルギーの理解と対話増進のための「温度」に関するワークショップの開発2025 · 2025年10月 ～ 2026年2月
• 代謝機構および間質との相互関連解明による膵癌幹細胞を標的とした治療法の確立佐藤 賢一, 横山 美沙, 渋谷 莉恵

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