東京科学大学 · 医歯学総合研究科

研究キーワードallogeneic transplant complications・adenovirus hepatitis・anti-DNA antibodies・TLR9 signaling・beta2-glycoprotein I autoantibodies・lupus pathogenesis

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• Tomoda, T; Nishimura, A; Kamiya, T; Inoue, K; Katano, H; Iida, S; Hoshino, A; Isoda, T; Imai, K; Kajiwara, M; Takagi, M; Kanegane, H; Hanaoka, N; Morio, T. Immune reconstitution and cidofovir administration rescue human adenovirus hepatitis after allogeneic hematopoietic cell transplantation TRANSPLANT IMMUNOLOGY. 2024.10; 86 102093. ( PubMed , DOI )2024
• Masumi Saito, Yumi Makino, Kumi Inoue, Yoshino Watanabe, Osamu Hoshi, Tetsuo Kubota. Anti-DNA antibodies cross-reactive with β 2-glycoprotein I induce monocyte tissue factor through the TLR9 pathway. Immunol Med. 2021.06; 44 (2): 124-135. ( PubMed , DOI )2021
• K Inoue, M Ishizawa, T Kubota. Monoclonal anti-dsDNA antibody 2C10 escorts DNA to intracellular DNA sensors in normal mononuclear cells and stimulates secretion of multiple cytokines implicated in lupus pathogenesis. Clin Exp Immunol. 2020.02; 199 (2): 150-162. ( PubMed , DOI )2020
• S Virachith, M Saito, Y Watanabe, K Inoue, O Hoshi, T Kubota. Anti-β2-glycoprotein I antibody with DNA binding activity enters living monocytes via cell surface DNA and induces tissue factor expression. Clin Exp Immunol. 2019.02; 195 (2): 167-178. ( PubMed , DOI )2019

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