東京科学大学 · 総合研究院 · 助教

研究キーワードintestinal autophagy・inflammatory bowel disease・nickel-induced inflammation・ubiquitin signaling・focal adhesion remodeling

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• Tsujioka, M; Miyazawa, K; Ohmuraya, M; Nibe, Y; Shirokawa, T; Hayasaka, H; Mizushima, T; Fukuma, T; Shimizu, S. Identification of a novel type of focal adhesion remodelling via FAK/FRNK replacement, and its contribution to cancer progression CELL DEATH & DISEASE. 2023.04; 14 (4): 256. ( PubMed , DOI )2023
• Tamura A, Ito G, Matsuda H, Nibe-Shirakihara Y, Hiraoka Y, Kitagawa S, Hiraguri Y, Nagata S, Aonuma E, Otsubo K, Nemoto Y, Nagaishi T, Watanabe M, Okamoto R, Oshima S. Zranb1-mutant mice display abnormal colonic mucus production and exacerbation of DSS-induced colitis. Biochemical and biophysical research communications. 2022.11; 628 147-154. ( PubMed , DOI )2022
• Matsuda H, Nibe-Shirakihara Y, Tamura A, Aonuma E, Arakawa S, Otsubo K, Nemoto Y, Nagaishi T, Tsuchiya K, Shimizu S, Ma A, Watanabe M, Uo M, Okamoto R, Oshima S. Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice. Biochemical and biophysical research communications. 2022.02; 592 74-80. ( PubMed , DOI )2022
• Aonuma, E; Tamura, A; Matsuda, H; Asakawa, T; Sakamaki, Y; Otsubo, K; Nibe, Y; Onizawa, M; Nemoto, Y; Nagaishi, T; Tsuchiya, K; Nakamura, T; Uo, M; Watanabe, M; Okamoto, R; Oshima, S. Nickel ions attenuate autophagy flux and induce transglutaminase 2 (TG2) mediated post-translational modification of SQSTM1/p62 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021.02; 542 17-23. ( PubMed , DOI )2021

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