東京科学大学 · 医歯学総合研究科 · 助教

研究キーワードRNA binding proteins・post transcriptional regulation・inflammation・PD L1 regulation・breast cancer stem cells・mechanotransduction・periodontal ligament・HIF1alpha・chondrogenesis・Sox9

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• Masayasu Sega, Yutaro Uchida, Tomoki Chiba, Takahide Matsushima, Kohei Kita, Naoyuki Miyasaka, Hiroshi Asahara. Stage- and cluster-specific regulation of chondrogenic gene programs by Sox9 in mouse embryonic limb buds. iScience. 2026.03; 29 (3): 115074. ( PubMed , DOI )2026
• Junya Ito, Kensuke Miyake, Tomoki Chiba, Kazufusa Takahashi, Yutaro Uchida, Perry J Blackshear, Hiroshi Asahara, Hajime Karasuyama. Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses. Allergol Int. 2025.04; 74 (2): 263-273. ( PubMed , DOI )2025
• Suzu Chida, Tomoki Chiba, Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Takayuki Miyazaki, Lisa Yagasaki, Satoshi Nakamura, Emiko Mihara, Junichi Takagi, Keiji Moriyama, Hiroshi Asahara. Impact of mechanotransduction on gene expression changes in periodontal ligament during orthodontic tooth movement. J Bone Miner Metab. 2025.02; ( PubMed , DOI )2025
• Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Goshi Oda, Iichiroh Onishi, Yasuto Takeuchi, Noriko Gotoh, Hiroshi Asahara. RNA binding protein ZCCHC24 promotes tumorigenicity in triple-negative breast cancer. EMBO Rep. 2024.12; 25 (12): 5352-5382. ( PubMed , DOI )2024

• 乳癌幹細胞を標的にした新規人工核酸医薬の開発
• ncRNAネオタクソノミのための大規模解析基盤の開発

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