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研究キーワードbisphenol A・cadmium toxicity・trophoblast differentiation・extravillous trophoblasts・placental toxicology・metallothionein expression・epigenetic regulation・HLA-G

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• Environmentally relevant low-dose bisphenol A enhances invasion of human extravillous trophoblasts with associated increases in MMP activity2026 · Reproductive Toxicology
• The Difference in Zinc Concentrations Required for Induction among Metallothionein Isoforms Can Be Explained by the Different MTF1 Affinities to MREs in Its Promoter2022 · International Journal of Molecular Sciences
• Cadmium inhibits differentiation of human trophoblast stem cells into extravillous trophoblasts and disrupts epigenetic changes within the promoter region of the HLA-G gene2022 · Toxicological Sciences
• Cadmium inhibits forskolin-induced differentiation of human placental BeWo cells2022 · The Journal of Toxicological Sciences

• エピ変異原曝露による胎盤細胞毒性発現メカニズムの解明と新規バイオマーカーの同定2023 · 科学研究費助成事業

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