東京大学 · 薬学系研究科・薬学部 · 特任助教

研究キーワードNMR spectroscopy・protein dynamics・oligomeric proteins・conformational equilibrium・G proteins・potassium channels・DegP protease・methyl-TROSY

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• Exploring Host–Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR
• Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties
• Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP
• Measurement of 1Hα transverse relaxation rates in proteins: application to solvent PREs

• Functional Design of Intrinsically Disordered Proteins Guided by NMR Electrostatic Potential Measurements
• Faculty of 1000 evaluation for "NMR Method for Characterizing Microsecond-to-Millisecond Chemical Exchanges Utilizing Differential Multiple-Quantum Relaxation in High Molecular Weight Proteins"
• ミトコンドリアプロテアーゼHtrA2の活性化機構の解明
• DDXヘリカーゼによるRNA構造リモデリング機構の解明

• 公式プロフィール