植草学園大学 · 保健医療学部

研究キーワード・アルツハイマー病モデル動物における認知機能障害の検討 ・アルツハイマー病に対する非薬物介入の効果と脳内メカニズムの解明・医学・歯学・薬学・保健

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• 1. Mulberry fruit extract alleviates the intracellular amyloid-β oligomer-induced cognitive disturbance and oxidative stress in Alzheimer’s disease model mice.Tomoyo Ochiishi, Masami Kaku,Tauwarat Kajsongkram & Krittiya Thisayakorn; Genes to Cells, Vol.26, Issue 11, p.861-873, 20212021
• 2.New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers. Tomoyo Ochiishi, Masami Kaku, Kazuyuki Kiyosue, Motomichi Doi, Takao Urabe, Nobutaka Hattori, Hideki Shimura & Tatsuhiko Ebihara; Scientific Reports 9, 2019. Article number2019
• 3.Can rats control previously acquired spatial information? Evidence of “ directed forgetting” phenomenon in delay-iterposed radial maze behavior. Masami Kaku, Kazuo Yamada, Yukio Ichitani; Behavioural Brain Research，248， pp. 1-6，20132013
• 4.Effects of intrahippocampal cannabinoid receptor agonist and antagonist on radial maze and T-maze delayed alternation performance in rats. Toshiko Suenaga, Masami Kaku, Yukio Ichitani; Pharmacology, Biochemistry and Behavior，91，pp. 91-96，20082008

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