北海道情報大学 · 医療情報学科/医療情報学部

研究关键词ウイルスによる発がん機構 | RNAと細胞がん化メカニズム | 腫瘍溶解ウイルス開発・Oncolytic・virus

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• 4. Kuroshima T., Aoyagi M., Yasuda M., Kitamura T., Jehung J.P., Ishikawa M., Kitagawa Y., Totsuka Y., Shindoh M. and Higashino F. Viral mediated stabilization of AU-rich element containing mRNA contributes to cell transformation. Oncogene, 30, 2912-2920 (2011).2011
• 5. Higashino F., Aoyagi M., Takahashi A., Ishino M., Taoka M., Isobe T., Kobayashi M., Totsuka Y., Kohgo T. and Shindoh M. Adenovirus E4orf6 targets pp32/LANP to control the fate of ARE-containing mRNAs by perturbing the CRM1-dependent mechanism. J. Cell Biol. 170, 15-20 (2005).2005
• 6. Takahashi A., Higashino F., Aoyagi M., Yoshida K., Itoh M., Kyo S., Ohno T., Taira T., Ariga H., Nakajima K., Hatta M., Kobayashi M., Sano H., Kohgo T. and Shindoh M. EWS/ETS fusions activate telomerase in Ewing’s tumors. Cancer Res. 63, 8338-8344 (2003).2003
• 7. Aoyagi M., Higashino F., Yasuda M., Takahashi A., Sawada Y., Totsuka Y., Kohgo T., Sano H., Kobayashi M. and Shindoh M. Nuclear export of the adenovirus E4orf6 protein is necessary for its ability to antagonize the apoptotic activity of the BH3-only proteins. Oncogene 22, 6919-6927 (2003).2003

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