Makizako H., Shiratsuchi D., Miyake Y., Tabira K., Tateishi M., Akaida S., Nishi H., Fukumori M., Baba Y., Kobayashi M., Takihara T. . Effects of catechin-enriched green tea combined with exer2026 · 記述言語： 日本語 出版者・発行元： Archives of Gerontology and Geriatrics Background: Catechin could improve physical performance through enhanced muscle recovery and mitochondria function. Clinical evidence regarding the effect of catechin supplementation on muscle strength and physical performance in older adults remains scarce. Objectives: This community-based randomized controlled trial investigated the effects of catechin-enriched green tea combined with exercise on physical performance and muscle mass in community-dwelling older adults. Methods: Seventy-eight adults aged ≥60 years who perceived themselves as experiencing weakness or slowness were randomly assigned to either an intervention group (exercise plus catechin-enriched green tea, n = 45) or a control group (exercise plus placebo, n = 33). All participants attended regular community self-management group exercise classes and a supplementary 60 min exercise session once per month. The intervention group consumed catechin-enriched green tea, providing 613 mg of catechin per day for 24 weeks. Results: Fifty-one of the 78 randomized participants completed the trial with high adherence (≥60%). In the intent-to-treat analysis, there were no statistically significant differences in physical performance tests or muscle mass between the groups at pre- and post-intervention assessments by the linear mixed-effects models. The percentage change in knee extension strength over 24 weeks differed significantly between the intervention and control groups (P = 0.016). Catechin-enriched green tea intake was associated with changes in Titin N-terminal fragment. Conclusions: The combination of catechin-enriched green tea and exercise had a beneficial effect on lower limb muscle strength in community-dwelling older adults who perceived a decline in physical performance. DOI： 10.1016/j.archger.2026.106260 Scopus PubMed
