明治薬科大学 · 未分類 · 講師

研究关键词retinoid X receptor・AMP-activated protein kinase・constitutive androstane receptor・CYP2B induction・PXR signaling・hypoxia-inducible factor・estrogen receptor alpha・energy metabolism

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• Phosphorylation of estrogen receptor in reproductive organs of female mice
• A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice.
• A physiological role of AMP-activated protein kinase in phenobarbital-mediated constitutive androstane receptor activation and CYP2B induction.
• Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils.

• エストロゲン受容体機能のリン酸化による制御：肥満や神経変性疾患予防への応用
• 転写因子TCF3によるメチル水銀毒性軽減機構の解明

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