信州大学 · 医学科/医学部 · 講師

研究关键词cerebral hypoperfusion・misery perfusion・awake mouse PET・cortical microvasculature・chronic hypoxia angiogenesis・experimental autoimmune encephalomyelitis・neuromyelitis optica・Rho kinase・spinal cord injury・neuronal survival

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• AMSH, an ESCRT-III associated enzyme, deubiquitinates cargo on MVB/late endosomes
• ESCRT-0 Protein Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate (Hrs) Is Targeted to Endosomes Independently of Signal-transducing Adaptor Molecule (STAM) and the Complex Formation with STAM Promotes Its Endosomal Dissociation
• Angiotensin II activates Ca(V)1.2 Ca2+ channels through beta-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes
• EF-1α and Mitochondrial ATP Synthase β Chain: Alteration of Their Expression in Encystment-Induced Colpoda cucullus

• 胆管癌幹細胞に高発現するS100分子群の癌悪性形質維持機構の解明
• 脱ユビキチン化酵素ＡＭＳＨによる細胞内小胞輸送の制御機構の解析
• 胆管癌の浸潤転移能獲得におけるS100A10の機能解明と治療戦略への展開
• 進行がんを制圧する分子進化型人工サイトカイン医薬の開発

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