帝京大学 · 薬学部

研究关键词galectin-2・galectin-1・glycoprotein crosslinking・photoaffinity labeling・Caenorhabditis elegans glycobiology・mucin interactions・S-nitrosylation・Helicobacter pylori agglutination

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• Preparation of a polyclonal antibody that recognizes a unique galactoseβ1-4fucose disaccharide epitope.
• S-nitrosylation of mouse galectin-2 prevents oxidative inactivation by hydrogen peroxide
• Side Chain Orientation of the Amino Acid Substituted by a Cysteine Residue Is Important for Successful Crosslinking of Galectin to Its Glycoprotein Ligand Using a Photoactivatable Sulfhydryl Reagent
• N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation

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