東京科学大学 · 総合研究院

研究关键词Mitophagy・Pexophagy・PINK1-parkin pathway・mitochondrial ubiquitination・p97/VCP・OPTN-ATG9A Axis・DJ-1・TBK1-NDP52 Signaling・selective autophagy

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• UFD1 Recognition of Initiator and Proximal Ubiquitin Drives p97-Mediated Substrate Unfolding enhanced by FAF1, FAF2, and UBXD7 2026.03; ( DOI )2026
• Fumika Koyano, Noriyuki Matsuda. Quality control of ABCD3 by the VCP-FAF2 complex suppresses excessive pexophagy. Autophagy. 2025.02; 21 (5): 1169-1170. ( PubMed , DOI )2025
• Watanabe A, Ogiwara S, Saito M, Mishima M, Yamashina M, Ishitani R, Ito Y, Tanaka K, Koyano F, Yamano K, Kosako H, Moriwaki Y, Matsuda N. The reaction mechanism for glycolysis side product degradation by Parkinson's disease-linked DJ-1. Journal of Cell Biology. 2025.08; 224 (8): e202411078.. ( PubMed , DOI )2025
• Norizuki T, Kushida Y, Sekimoto T, Sasaki T, Yamano K, Matsuda N, Sasaki R, Noda NN, Sato K, Sato M. ALLO-1a is a ubiquitin-binding adaptor for allophagy in Caenorhabditis elegans. Journal of Cell Science. 2025.12; 138 (24): jcs264252.. ( PubMed , DOI )2025

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