東京科学大学 · 歯学部

研究关键词oral lichenoid lesions・oral tongue squamous cell carcinoma・tumor immune microenvironment・multiplex immunofluorescence・machine learning pathology

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• Naoto Nishii,Fumihiko Tsushima,Jinkyo Sakurai,Yuya Su,Naoya Kinoshita,Yu Oikawa,Yosuke Hirotsu,Toshimitsu Ohsako,Emi Furusawa-Nishii,Masao Omata,Hiroyuki Harada. TCR repertoire analysis reveals predominant local clonal expansion of T cells with minimal circulation in oral lichenoid contact lesions Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2025.08; ( DOI )2025
• Yuya Su, Ryo Ouchi, Pissacha Daroonpan, Miwako Hamagaki, Tohru Ikeda, Noji Rika, Naoto Nishii, Fumihiko Tsushima, Yoshihito Kano, Takahiro Asakage, Makoto Noguchi, Hiroyuki Harada, Miyuki Azuma. Stratification of the immunotypes of tongue squamous cell carcinoma to improve prognosis and the response to immune checkpoint inhibitors. Cancer Immunol Immunother. 2025.03; 74 (4): 130. ( PubMed , DOI )2025
• Akaike Y, Morita KI, Sakamoto K, Tsushima F, Kayamori K, Maruta N, Yamazaki K, Anzai E, Tonouchi E, Harada H, Ikeda T, Yoda T. Automatic detection of spongiosis associated with oral lichenoid lesions using machine learning J Oral Maxillofac Surg, Med, Pathol. 2023.07; 35 (4): 368-374. ( DOI )2023
• Pissacha Daroonpan, Ryo Ouchi, Chenyang Zhang, Shigenori Nagai, Naoto Nishii, Yoshihisa Kashima, Fumihiko Tsushima, Hiroyuki Harada, Miwako Hamagaki, Tohru Ikeda, Jun Aida, Ruchadaporn Kaomongkolgit, Miyuki Azuma. Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence. Oral Oncol. 2023.08; 143 106458. ( PubMed , DOI )2023

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