東北大学 · 薬学部 / 薬学研究科 · 助教

研究关键词antibody engineering・humanized mouse models・monoclonal antibodies・mammalian display・SARS-CoV-2 antibodies・antibody-drug conjugates・BRCA-mutant ovarian epithelium

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• Rapid immunization and antibody redesign platform discovers broadly neutralizing antibodies against non-immunized SARS-CoV-2 variant.Shusei Hamamichi, Narumi Uno, Kazuto Shimoya, Takato Fukushima, Marina Abe, Arata Watanabe, Mizuho Ito, Yuko Wakasa, Yuko Yajima, Rio Suzuki, Natsumi Miyazaki, Akifumi Kamiyama, Kana Uno, Masaharu Hiratsuka, Takashi Moriwaki, Tomokazu Tamura, Kyosuke Kanai, Satoshi Abe, Takasuke Fukuhara, Seiji Kageyama, Masayuki Su'etsugu, Yasuhiro Kazuki, Kazuma Tomizuka
• Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation.Hiroaki Komatsu, Masayo Okawa, Yasuhiro Kazuki, Kanako Kazuki, Genki Hichiwa, Kazuto Shimoya, Shinya Sato, Fuminori Taniguchi, Mitsuo Oshimura, Tasuku Harada
• Mice carrying the full-length human immunoglobulin loci produce antigen-specific human antibodies with the lambda light chainKazuto Shimoya, Takashi Moriwaki, Kanako Kazuki, Akane Okada, Shigenori Baba, Yuana Masuda, Satoshi Abe, Yasuhiro Kazuki
• Characterization of human anti-EpCAM antibodies for developing an antibody-drug conjugate.Hiroyuki Satofuka, Yayan Wang, Kyotaro Yamazaki, Shusei Hamamichi, Takeshi Fukuhara, Abdur Rafique, Nana Osako, Iori Kanazawa, Takeshi Endo, Naomi Miyake, Kazuhisa Honma, Yuichi Nagashima, Genki Hichiwa, Kazuto Shimoya, Satoshi Abe, Takashi Moriwaki, Yasufumi Murakami, Xu Gao, Hiroyuki Kugoh, Mitsuo Oshimura, Yuji Ito, Yasuhiro Kazuki

• mRNA免疫技術を活用した抗体取得プロセス開発下谷 和人

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