東北大学 · 医学部 / 医学系研究科 · 助教

研究关键词pain neurophysiology・entorhinal dopamine・Alzheimer disease models・gastric hyperalgesia・mechanical hypersensitivity・muscarinic M1 receptors・spinal sensory neurons・nerve injury models

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• Early dopamine disruption in the entorhinal cortex of a knock-in model of Alzheimer’s disease
• Responsiveness of lumbosacral superficial dorsal horn neurons during the voiding reflex and functional loss of spinal urethral-responsive neurons in streptozotocin-induced diabetic rats.
• Dopamine facilitates associative memory encoding in the entorhinal cortex
• Topical thermal therapy with hot packs suppresses physical inactivity-induced mechanical hyperalgesia and up-regulation of NGF.

• Circuit mechanisms underlying associative memory impairment in APP-KI mice Alzheimer's Association
• Understanding neural circuit mechanisms for associative memory impairment in APP-KI mice” BrightFocus Foundation

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