静岡県立大学 · 薬学研究院/薬学部 · 助教

研究关键词cocrystal inhalation powders・spray drying・ternary phase diagrams・simultaneous pulmonary delivery・amorphous formulations・polyphenol solubility・drug permeability

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• Effect of Solubility Improvement via Formation of an Amorphous Composite of Indomethacin and Sulindac on Membrane Permeability.
• Mixed micelles of the antihistaminic cationic drug diphenhydramine hydrochloride with anionic and non-ionic surfactants show improved solubility, drug release and cytotoxicity of ethenzamide
• Designing amorphous formulations of polyphenols with naringin by spray-drying for enhanced solubility and permeability
• Protectant Selection for Freeze Dry of Functional Peptide-Assembled Polymer Nanoparticles Composed of Methoxy Poly Ethylene Glycol ε-poly Caprolactone as a Carrier of Oligonucleotides

• 微粒子コーティングプロセスを利用したコアモルファス粒子設計技術基盤の構築
• コアモルファス形成に基づく粉末物性改善の開発

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