東京科学大学 · 医歯学総合研究科 · 教授

研究关键词Plasmodium falciparum・Plasmodium vivax transmission・rhoptry proteins・sporozoite liver infection・gametocyte biology・transmission-blocking immunity・malaria vaccine targets・parasite genome editing・ookinete crystalloid proteins・mosquito vector competence

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• Takashi Sekine, Naoaki Shinzawa, Rie Kubota, Daisuke Kobayashi, Yawara Okubo, Kentaro Itokawa, Haruhiko Isawa, Hisako Amino, Tomoko Ishino. A versatile, marker-free platform for life cycle-wide imaging in Plasmodium falciparum via integration of an exogenous gene cassette into a conserved intergenic locus 2026.01; ( DOI )2026
• Takashi Kumagai, Masaaki Miyamoto, Yurino Koseki, Yasuyuki Imai, Tomoko Ishino. Development of a spirulina feed effective only for the two larval stages of Schistosoma mansoni, not the intermediate host mollusc. Tropical medicine and health. 2025.04; 53 (1): 46. ( PubMed , DOI )2025
• Haghighi, T; Najer, A; Broto, M; Dahalan, FA; Churchyard, A; Yahiya, S; Famodimu, MT; Tunnicliff, M; Abdelwahed, A; Tachibana, M; Ishino, T; Aniweh, Y; Awandare, GA; Mahamar, A; Vanheer, LN; Bousema, T; Drakeley, C; Dicko, A; Stone, W; Baum, J; Stevens, MM. Evaluation of Malaria Parasite Transmission Competency Using a Nanozyme-Based Immunodiagnostic Targeting Female Gamete Antigen Release ACS NANO. 2025.10; 19 (41): 36419-36434. ( PubMed , DOI )2025
• Morita M, Jennison C, O'Neill MT, Kanoi BN, Ishino T, Tsuboi T, Boddey JA, Takashima E. Plasmodium falciparum Liver Stage Antigen 3 plays a role in completing the final stages of merozoite invasion of red blood cells. International journal for parasitology. 2025.10; ( PubMed , DOI )2025