Akita Prefectural University · Department of Applied Biological Science · 教授

Research keywordsMouse iPS cells・Cumate gene switch・PiggyBac transposon・Fibroblast growth factor 4・Homeoprotein TPRX1・Embryonal carcinoma cells・Cardiomyogenesis・Morpholino knockdown・Kasugamycin biosynthesis

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• Generation of mouse iPS cells using an inducible expression of transgenes via the cumate gene-switch2020
• Site-directed mutagenesis of cysteine to serine residues affects heparin binding and mitogenicity in fibroblast growth factor 4 produced in Escherichia coli2019
• Exogenous TPRX1 homeoprotein modulates the gene expression of lineage-specific transcription factors in human embryonal carcinoma cells2018
• Lipoprotein profiles of hepatic cell lines at various stages of differentiation2017

• 新規転写因子ＥＧＡＭ１タンパク質群を中心とする新たな胚発生制御機構の包括的理解（課題番号23K05510）2023
• 黒毛和種からのiPS細胞の全遺伝子解析による特徴の解明と始原生殖細胞への分化誘導2021
• 新規転写因子ＥＧＡＭ１ホメオタンパク質群を主軸とする胚発生制御の統合的理解（課題番号19K06373）2019
• 新規転写因子ＥＧＡＭ１ホメオタンパク質群による遺伝子発現と胚発生制御の分子基盤（課題番号16K07993）2016

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