Akita Prefectural University · Department of Applied Biological Science · 教授

Research keywords内分泌・低酸素病態・シナプス小胞・酸素応答・ペプチドホルモン・生体イメージング・分泌顆粒

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• IDENTIFICATION AND FUNCTIONAL EXPRESSION OF A NEW MEMBER OF THE MAMMALIAN KEX2-LIKE PROCESSING ENDOPROTEASE FAMILY - ITS STRIKING STRUCTURAL SIMILARITY TO PACE4
• The sorting mechanism to secretory granules: Emerging concepts with secretogranin III
• A subset of p23 localized on secretory granules in pancreatic beta-cells
• PACE4A IS A UBIQUITOUS ENDOPROTEASE THAT HAS SIMILAR BUT NOT IDENTICAL SUBSTRATE-SPECIFICITY TO OTHER KEX2-LIKE PROCESSING ENDOPROTEASES

• ホルモン前駆体と活性化酵素群が出会う仕組み：グラニンを介した共輸送機構の解明
• 分泌細胞における細胞極性の再定義：ゴルジ装置の大局的構造を新たな指標として
• トランスゴルジネットワークにおけるタンパク質の選別輸送機構
• 神経内分泌細胞の調節性分泌経路へのタンパク質選別輸送機構の解明

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