Chiba University · Graduate School of Pharmaceutical Sciences · 講師

Research keywords放射性薬剤・分子イメージング・211At-labeled・alpha-melanocyte・stimulating・hormone・peptide・analog

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• Attempts to Improve the In vivo Stability of At-211 Labeled Agents
• Coordination-Mediated Synthesis of Purification-Free Bivalent 99mTc-Labeled Probes for in Vivo Imaging of Saturable System
• Synthesis and evaluation of a para-carboxylated benzyl-DOTA for labeling peptides and polypeptides
• Delivery of aPD-L1 antibody to i.p. tumors via direct penetration by i.p. route: Beyond EPR effect

• 悪性黒色腫の標的α線治療を指向するAt-211標識薬剤開発
• 体内動態を制御したAt－211標識アミノ酸による汎用的α線治療法の創出
• At-211を用いる内用放射線治療に適した抗体フラグメント標識薬剤の開発
• At-211標識アミノ酸誘導体によるLAT1を標的とした新規RI内用療法の開発

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