Ehime Prefectural University of Health Sciences · Department of Clinical Laboratory Science · 教授

Research keywordsCD8 T cells・tumor immunology・T-cell metabolism・memory T cells・glutamine restriction・menin・glycolysis・hematologic immunology

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• Enhancement of antitumor activity by epigenetic regulation of tumour-specific T cells2021
• T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses.2020
• Histone H3K27 demethylase negatively controls the memory formation of Ag-stimulated CD8+ T cells.2019 · Journal of immunology
• The tumor suppressor menin prevents effector CD8 T cell dysfunction via metabolic restriction by targeting mTOR activation.2018 · Nature Communications

• 小胞体ストレス応答蛋白 IRE1αに焦点を当てたT細胞の抗腫瘍活性の増強2024
• ヒストン脱メチル化酵素Phf2の制御を介したT細胞抗腫瘍免疫の増強2023
• 新規一本鎖抗体作製技術を用いた多機能的CAR-T細胞療法の開発研究2022
• 細胞内エネルギー代謝調節による効果的なT細胞免疫療法の開発2020

• Official profile