Fukui Prefectural University · Department of Bioresources / Graduate School of Bioresources · 教授

Research keywords放線菌・生合成・Actinomycetes・Biosynthesis・微生物・天然物・二次代謝産物・Secondary metabolites

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• Separation of an ε-poly-L-lysine derivative by solvent extraction under a controlled interfacial potential difference.
• First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
• Desensitization of feedback inhibition of the Saccharomyces cerevisiae gamma-glutamyl kinase enhances proline accumulation and freezing tolerance
• NRPSs and amide ligases producing homopoly(amino acid)s and homooligo(amino acid)s

• 天然ペプチド系化合物に構造・機能多様性をもたらす新規酵素・生合成機構の解明と応用
• 生物活性中高分子の革新的細胞内送達技術による細胞生理機能の制御
• 抗生物質ストレプトスリシン生合成酵素を利用した生理活性物質の膜透過性向上への試み
• 天然PIECE抱合法による生理活性ペプチドの消化管吸収への挑戦

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