Fujita Health University · Faculty of Medicine / Graduate School of Medicine · 教授

Research keywordscancer molecular biology・DNA replication stress・DNA repair genes・prostate cancer metabolism・cancer stem cell interaction・oncogenic mutation mechanisms・DNA polymerase biology

Research fieldsRespiratory organ internal medicine・Tumor biology

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• MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis
• Cellular concentrations of plasmalogen species containing a polyunsaturated fatty acid significantly increase under hypoxia in human colorectal cancer, Caco2 cells
• Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
• DNA polymerase α overcomes an error-prone pause site in the presence of replication protein-A

• 東南アジアにおける新型ヒトマラリアの疫学調査
• PD-L1発現におけるYB1の機能解析：免疫チェックポイント療法の発展をめざして
• 肺がん転移を制御するセラミドホメオスタシス解明とその応用
• DNA複製・複製後DNA修復が細胞ゲノム統合性・発癌抑制に与える影響

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