Gifu University · Faculty of Engineering · 准教授

Research keywordstRNA synthetases・tRNA modification・genetic code expansion・unnatural amino acids・Escherichia coli expression systems・Trm1 methyltransferase・tRNA-guanine transglycosylase

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• Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase
• A base pair at the bottom of the anticodon stem is reciprocally preferred for discrimination of cognate tRNAs by Escherichia coli lysyl- and glutaminyl-tRNA synthetases
• Boosting Auto-induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives.
• Use of RNase P for efficient preparation of yeast tRNA(Tyr) transcript and its mutants

• 細胞表層工学を用いたアレルゲンコンポーネントに対する抗体の簡便な選別法の確立
• プロ酵素の不活性状態を生み出す分子機構の解明と創薬への応用
• 非標準アミノ酸を利用した光開閉制御可能なバイオ・ナノカプセルの開発
• 非天然型アミノ酸を利用した部位指定タンパク質1分子1蛍光標識法の開発

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