Gifu University · Graduate School of Medical Sciences

Research keywordsleukemia metabolism・glycolysis and TCA cycle・glutamine metabolism・oxidative phosphorylation・FLT3-ITD leukemia・diffuse large B-cell lymphoma・hypoxia-driven proliferation・CRISPR genome editing・immune thrombocytopenia・leukemia cell lines

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• Growth of xenotransplanted leukemia cells is influenced by diet nutrients and is attenuated with 2-deoxyglucose.
• Arsenic trioxideはJAK-STATシグナル経路の阻害によりSOCS3発現を抑制する(Arsenic trioxide prevents SOCS3 expression by inhibiting JAK-STAT signaling pathway)
• High-resolution 400K oligonucleotide array comparative genomic hybridization analysis of neurofibromatosis type 1-associated cutaneous neurofibromas.
• Lipopolysaccharide augments the uptake of oxidized LDL by up-regulating lectin-like oxidized LDL receptor-1 in macrophages.

• 亜ヒ酸による特異的移植片対宿主病予防・治療法の開発

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