Gifu University · Faculty of Applied Biological Sciences · 教授

Research keywords出芽酵母・グリセロリン脂質・生体膜・脂質生化学・酵母遺伝学・スフィンゴ脂質

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• Protection mechanisms against aberrant metabolism of sphingolipids in budding yeast
• O-glycosylation of mucin-like domain retains the neutral ceramidase on the plasma membranes as a type II integral membrane protein
• Overexpression of PDR16 confers resistance to complex sphingolipid biosynthesis inhibitor aureobasidin A in yeast Saccharomyces cerevisiae
• Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling

• 生体膜スフィンゴ脂質の代謝破綻から細胞を守る新規救済機構の解明
• スフィンゴ脂質シグナル生成機構のメタボローム解析
• 細胞外スフィンゴ脂質シグナルの生成機構およびその生物機能の解析
• 酵母生体膜スフィンゴ脂質の構造多様性と環境ストレス応答の連関の解明と応用

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