Gifu University · Faculty of Applied Biological Sciences · 教授

Research keywordsRNAi・siRNA・核酸医薬・核酸・ヌクレオチド・ヌクレオシド・オリゴヌクレオチド・DNA・miRNA・Organic Chemistry of Nucleic Acids

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• Crystal structures of DNA : DNA and DNA : RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules
• Preparation of O-phosphoryl amino acid building blocks for the synthesis of O-phosphoryl peptides
• 4′‐C‐Aminoethoxy‐Modified DNAs Exhibit Increased Nuclease Resistance, Sustained RNase H Activity, and Inhibition ofKRASGene Expression
• Synthesis and hybridization properties of oligonucleotides containing (2S,3R)-9-(2,3,4-trihydroxybutyl)adenine

• C型肝炎ウイルスを標的とする新規siRNAの開発
• 修復酵素AlkAの損傷塩基を含むDNA認識様式の解析
• 食品タンパク質由来の脂質代謝改善ペプチドに関する基盤的研究
• アンチセンス・アンチジーンオリゴヌクレチドの合成研究

• Official profile