Hamamatsu University School of Medicine · Department of Third Internal Medicine

Research keywordsmitochondrial permeability transition pore・cardiomyocyte lipotoxicity・AMP kinase signaling・GSK-3beta signaling・intracellular renin・diabetic heart ischemia

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• Glycogen synthase kinase-3β opens mitochondrial permeability transition pore through mitochondrial hexokinase II dissociation.
• Intracellular Renin Inhibits Mitochondrial Permeability Transition Pore via Activated Mitochondrial Extracellular Signal-Regulated Kinase (ERK) 1/2 during Ischemia in Diabetic Hearts.
• Recurrent Coronary Thrombus in a Patient with Chronic Immune Thrombocytopenia with Treatment Using Eltrombopag.
• Eicosapentaenoic acid ameliorates palmitate-induced lipotoxicity via the AMP kinase/dynamin-related protein-1 signaling pathway in differentiated H9c2 myocytes.

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