Health Sciences University of Hokkaido · Graduate School of Pharmaceutical Sciences · 准教授

Research keywords合理的設計に基づく新規機能性核酸分子の創製研究・核酸化学・核酸医薬・生物有機化学

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• The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside.2020 · Frontiers in microbiology
• Synthesis of 2-Amino-4-Fluoropyridine-C-Nucleoside Phosphoramidite for Incorporation into Oligonucleotides.2019 · Current protocols in nucleic acid chemistry
• Improvement of SN Ar Reaction Rate by an Electron-Withdrawing Group in the Crosslinking of DNA Cytosine-5 Methyltransferase by a Covalent Oligodeoxyribonucleotide Inhibitor.2018 · Chembiochem : a European journal of chemical biology
• Insight into the recognition mechanism of DNA cytosine-5 methyltransferases (DNMTs) by incorporation of acyclic 5-fluorocytosine (FC) nucleosides into DNA.2018 · Bioorganic & medicinal chemistry letters

• 化学修飾ヌクレオシドによる新規核酸ータンパク質架橋反応の開発2021 · 一般助成
• 芳香族求核置換反応を用いる新規核酸ータンパク質架橋剤の開発2020 · 薬学系研究助成
• RNA高次構造を検出可能な超効率的RNA検出プローブの開発2017 · 科学研究費補助金(基盤研究(C))
• 生細胞内クロスリンク反応によるDDSを用いない二本鎖核酸導入法の開発2013 · 科学研究費補助金(基盤研究(C))

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