Hokkaido University · Faculty of Fisheries Sciences / Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences · 准教授

Research keywordsクライオ電子顕微鏡・リボソーム・単粒子解析・超分子複合体・翻訳・RNA・Cryo・Synthesis

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• Synthesis and structure-activity relationship of azithromycin derivatives against non-tuberculous mycobacteria2026 · European Journal of Medicinal Chemistry, 304, 118520, 118520, Elsevier BV, 2026年02月,
• Glomerular routing of tumor-derived extracellular vesicles substantiates urinary biopsy.2026 · Science advances, 12, 8, eaeb0555, 2026年02月20日,
• Cryo-EM elucidates the interaction mechanism of ozoralizumab, a humanized anti-TNFα NANOBODY® compound2026 · Biochemical and Biophysical Research Communications, 816, 153572, 153572, Elsevier BV, 2026年06月,
• Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement2025 · Cell Reports, 44, 7, 115965, 115965, Elsevier BV, 2025年07月,

• 病原菌の鉄獲得プロセスの最上流で機能する膜孔形成毒素の分子機構の活写
• 革新的配糖化技術を基盤とした肺非結核性抗酸菌（NTM）症に対する新規抗菌物質の創製
• リボソームの動的分子構造と細胞内分布の統合的理解
• クライオ電子顕微鏡による、転写翻訳複合体の構造解析

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