Hokkaido University · Institute for Genetic Medicine · 教授

Research fields医化学・Neuroscience in general・Tumor biology

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• Carboxy terminal of ECRG4 is a potential initiator for amyloid pathology in Alzheimer’s disease through interacting with APP intracellular domain.2026 · J. Alzheimer’s Dis., 2026年,
• Fragment of esophageal cancer-related gene-4 induces lysosome-dependent cell death via cathepsin secretion in astrocytes2026 · Tissue and Cell, 102, 103553, 103553, Elsevier BV, 2026年10月,
• Neuronal Differentiation of GBM-Initiating Cells Combined with Elimination of Undifferentiated Cells Preserves Motor Function2026 · Cells, 15, 6, 539, 539, MDPI AG, 2026年03月18日,
• Plasma ECRG4 as a novel diagnostic marker for Alzheimer’s disease associated with oligodendrocyte dysfunction.2026 · Am. J. Transl. Res., 2026年,

• クロマチン制御因子がもたらす脳サイズ調節遺伝子ネットワークの解明
• 中枢神経系発生における分化抑制転写因子Id4の機能解析
• ヒトグリオーマ細胞株に存在する幹細胞様細胞の精製および新規マーカー遺伝子の単離
• 癌幹細胞を標的とした癌根絶療法の創出

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