Hokkaido University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences

Research keywordslipid nanoparticles・Cas9 ribonucleoproteins・mRNA vaccines・B-cell targeting・ionizable lipids・formulation stability

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• The effect of guide RNA thermal denaturation on the quality of Cas9 ribonucleoprotein-loaded lipid nanoparticle formulations2026 · RSC PHARMACEUTICS, 3, 1, 2026年01月27日
• Marginal-zone B cells as promising targets of an mRNA-loaded, lipid-nanoparticle cancer vaccine2025 · Next Nanotechnology, 8, 100154, 100154, Elsevier BV, 2025年
• Examining the Impact of Storage Conditions on the Stability of a Liquid Formulation of mRNA-Loaded Lipid Nanoparticles2025 · Pharmaceutics, 17, 9, 1194, 1194, MDPI AG, 2025年09月14日
• Splenic B cell-targeting lipid nanoparticles for safe and effective mRNA vaccine delivery.2025 · Journal of controlled release : official journal of the Controlled Release Society, 382, 113687, 113687, 2025年04月03日,

• 優れた保存安定性とmRNA導入効率を両立するLNP製剤の開発

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