Iwate Medical University · Unclassified · 准教授

Research keywords骨免疫学・C型レクチン受容体・サイトカイン・破骨細胞・糖鎖・自己免疫疾患

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• DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis.
• The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17.
• Novel mast cell lines with enhanced proliferative and degranulative abilities established from temperature-sensitive SV40 large T antigen transgenic mice
• Immunoglobulin-like receptors in myeloid cells: The functional regulation and the involvement in disorders

• 内在リガンド認識性抑制型C型レクチン受容体の生理機能と疾患関連の解明
• イムノグロブリン様受容体による免疫制御機構の研究
• 疾患のシステム的理解を目指したIL-1関連遺伝子欠損マウスライブラリーの作製
• 糖鎖認識受容体DCIRと糖鎖リガンドの相互作用による免疫応答制御の解明

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