Iwate Medical University · Faculty of Dentistry, Department of Microbiology (Division of Molecular Microbiology) · 教授

Research keywordsoral microbiology・streptococcal adhesion・fibronectin binding・endothelial interaction・salivary proteins

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• Epigallocatechin gallate stimulated histamine production and downregulated histamine H1 receptor in oral cancer cell lines expressing histidine decarboxylase.
• 分泌型白血球プロテアーゼインヒビターによる歯肉上皮細胞のPorphyromonas gingivalis感染制御
• Uptake of Nanotitania by Gingival Epithelial Cells Promotes Inflammatory Response and Is Accelerated by Porphyromonas gingivalis Lipopolysaccharide: An In Vitro Study.
• Establishment and use of a three-dimensional ameloblastoma culture model to study the effects of butyric acid on the transcription of growth factors and laminin β3.

• 癌関連口腔レンサ球菌由来抗原の感染発癌における病原性の解明
• 癌原性口腔レンサ球菌の発癌機序におけるヒト歯肉上皮ＡＩＤ異所性発現誘導
• ＳＬＰＩによるＰ．ｇｉｎｇｉｖａｌｉｓプロテアーゼ阻害作用と感染制御
• がん微小環境における腫瘍免疫破綻因子としての口腔細菌ジペプチダーゼ

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