Jichi Medical University · Faculty of Medicine, Department of Pediatrics

Research keywords発酵食品・脳・神経・Cadm1・旨味・D-アラニン・FOXP2・進化・自閉症

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• Synaptic adhesion molecules in Cadm family at the neuromuscular junction
• Total and reduced/oxidized forms of coenzyme Q10 in fibroblasts of patients with mitochondrial disease.
• ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
• Loss of partitioning-defective-3/isotype-specific interacting protein (Par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice

• 水産発酵食品の呈味有効成分とD型アミノ酸の味への寄与
• Foxp2による消化管・腸管神経系形成の分子機構と転写活性欠失変異の影響
• 低出生体重児のストレス反応とグルココルチコイドレセプター遺伝子DNAメチル化解析
• Ｇ蛋白結合型受容体とシナプスを標的とした共通病態基盤同定と自閉性障害治療法開発

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