Jichi Medical University · Faculty of Medicine, Department of Internal Medicine · 医学部内科学講座 アレルギー膠原病学部門 講師

Research keywords免疫学・遺伝学・リウマチ性疾患

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• Functional evaluation of rare OASL variants by analysis of SLE patient-derived iPSCs.
• Immature platelet levels correlate with disease activity and predict treatment response of thrombocytopenia in lupus patients.
• Rheumatoid arthritis in a patient with compound heterozygous variants in the COL11A2 gene and progressive hearing loss: A case report.
• Machine learning-driven immunophenotypic stratification of mixed connective tissue disease, corroborating the clinical heterogeneity.

• GWASとeQTLの統合解析による免疫疾患原因遺伝子の同定と機能解析
• Single-cell RNA-seqによる全身性強皮症の病原的免疫細胞の探索
• 関節リウマチを標的とした抗原特異的新規治療戦略の開発
• 関節リウマチの治療反応性予測バイオマーカーの確立と治療抵抗性機序の解明

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