Jichi Medical University · Graduate School of Medicine · 学長

Research keywordsmolecular biology・transcription factor・心血管病学・KLF5・cardiovascular disease・血管平滑筋・再狭窄・心不全

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• Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.
• Significance of Persistent Inflammation in Patients With Chronic Coronary Syndrome: Insights From the REAL-CAD Study.
• Characteristics of Chronic Rejection in Heart Transplantation: Important Elements of Pathogenesis and Future Treatments
• [Biochemical methods in the diagnosis of myocardial infarction (author's transl)].

• 心筋転写因子HOPの会合分子同定と心不全の分子機構解明
• 標的遺伝子組換えによる血管収縮ペプチド遺伝子欠損マウスの確立と病態解析への応用
• 血管の老化と平滑筋増殖を制御する遺伝子の同定
• 老化現象に伴う心筋虚血浸襲時の負荷応答: 新しい老化モデルマウスを用いた検討

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