Jichi Medical University · Graduate School of Medicine / Faculty of Medicine · 講師

Research keywordsIL-33・転移・動原体・シグナル伝達・質量分析・ST2・チェックポイント・生化学

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• The ORC1 cycle in human cells - II. Dynamic changes in the human ORC complex during the cell cycle
• STK38 Kinase Promotes Cell Migration Induced by Oncogenic Ras via MerTK Activation
• ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression
• ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant.

• Ras変異体が誘導する新規チロシンリン酸化シグナルとがん悪性化の新機構
• ＳＴ２タンパク質（分泌型ＩＬ－３３受容体）によるLPSシグナル阻害機構の解明
• Ras変異体が誘導する新規細胞遊走シグナルの分子基盤とがん悪性化への影響の解明
• 分泌型ST2タンパク質の炎症抑制機能部分の同定と創薬への応用

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