Jichi Medical University · Faculty of Medicine / Department of Biochemistry · 医学部生化学講座構造生化学部門 講師

Research keywordsミトコンドリアDNA・ミトコンドリア・RNA-processing・RNA・Mitochondria

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• Characterization of Bombyx mori mitochondrial transcription factor A, a conserved regulator of mitochondrial DNA
• Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites.
• Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates
• Inhibition of Malaria Infection in Transgenic Anopheline Mosquitoes Lacking Salivary Gland Cells

• 線虫をモデルとした変異型ミトコンドリアゲノムの分配・蓄積機構の解明
• TFAMを中心としたミトコンドリアゲノムの分配調節機構の解明
• Maintenance of mitochondrial genome, Mitochondrial RNA biology
• 神経性RNA結合タンパク質に着目した吸入麻酔薬の中枢性麻酔薬作用の解析

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