Jichi Medical University · Faculty of Medicine, Department of Internal Medicine · 内科学講座 内分泌代謝学部門 教授

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• Hepatic akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement
• Identification of Neutral Cholesterol Ester Hydrolase, a Key Enzyme Removing Cholesterol from Macrophages
• Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver
• Sterol Regulatory Element-Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

• 多価不飽和脂肪酸の作用ドメイン解明から新規高トリグリセリド血症治療薬へ
• 脂質代謝制御転写因子SREBP-1と-2の差異を同定するニュートリゲノミクス研究
• 脂肪酸伸長酵素Ｅｌｏｖｌ６による臓器脂質の質的変容と代謝病態の多臓器的展開
• 肥満治療を目指した細胞内脂質分解機構に関する分子生物学的研究

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