The Jikei University School of Medicine · Graduate School of Medicine / Faculty of Medicine

Research keywordscardiac calcium handling・sarcoplasmic reticulum・heart failure biomarkers・coronary physiology・mouse myocardium

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• Time-dependent changes in P2Y12 reaction unit values for predicting the different types of cardiovascular events in patients with ischemic heart disease.
• 拡張型心筋症マウスにおいて、アンジオテンシン受容体拮抗薬は収縮蛋白系Ca感受性の改善なしに心収縮力及び予後を改善する
• Genetic modulation of the SERCA activity does not affect the Ca(2+) leak from the cardiac sarcoplasmic reticulum.
• Alpha1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta1-adrenoceptor.

• 不全心筋における細胞内情報伝達系と細胞内カルシウム動態の変化

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