The Jikei University School of Medicine · Graduate School of Medicine / Faculty of Medicine · 准教授

Research keywordsantizyme・antizyme inhibitor・polyamine regulation・chaperonin GroEL・ubiquitin-independent proteasomal degradation・c-Myc turnover・ornithine decarboxylase

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• Multiple forms of mouse antizyme inhibitor 1 mRNA differentially regulated by polyamines.
• Regulation of ornithine decarboxylase by antizymes and antizyme inhibitor in zebrafish (Danio rerio)
• Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4.
• Identification of nuclear export signals in antizyme-1

• 神経芽細胞腫増殖におけるアンチザイム２とMYCNの相互作用の解析
• 細胞内ポリアミンの蛍光モニタリングシステムによるがん細胞の可視化
• アンチザイムの細胞内局在と相互作用分子の一細胞イメージング
• 膵臓がん細胞の低酸素応答における CDR2 とアンチザイム 2 の関与とその機序の解析

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