The Jikei University School of Medicine · Graduate School of Medicine / Faculty of Medicine · 准教授

Research keywordsDDS・Extracellular vesicles・Fibrosis・Translational medicine・Aging・Exosomes

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• Extracellular vesicle-mediated cellular crosstalk in lung repair, remodelling and regeneration.
• Single-cell Transcriptome Analysis Reveals an Anomalous Epithelial Variation and Ectopic Inflammatory Response in Chronic Obstructive Pulmonary Disease
• Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy.
• Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice.

• 腫瘍免疫応答を反映するがんエクソソーム迅速診断の基盤構築
• 特発性肺線維症に対するエクソソーム医薬品開発および実用化
• 非小細胞肺がん患者における腫瘍免疫応答を反映する体液診断技術
• COPDにおける新規２型肺胞上皮細胞サブグループを介した病態解明

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