The Jikei University School of Medicine · Graduate School of Medicine / Faculty of Medicine

Research keywords悪性黒色腫・遺伝性皮膚疾患・遺伝子治療・細胞療法・毛髪疾患・先天性表皮水疱症・人工多能性幹細胞・CRISPR/Cas9

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• Generation of induced pluripotent stem cell (iPSC) from NY-ESO-I-specific cytotoxic T cells isolated from the melanoma patient with minor HLAs: The practical pilot study for the adoptive immunotherapy for melanoma using iPSC technology.
• A novel mutation in the KCNJ8 gene encoding the Kir6.1 subunit of an ATP‐sensitive potassium channel in a Japanese patient with Cantú syndrome
• Novel mutation c.263A>G in the ACVRL1 gene in a Japanese patient with hereditary hemorrhagic telangiectasia 2.
• Successful treatment of disseminated superficial actinic porokeratosis with Q-switched ruby laser.

• 人工多能性幹細胞を用いた先天性表皮水疱症の治療法の確立
• 毛乳頭細胞におけるATP感受性カリウムイオンチャネルの役割
• 不死化毛乳頭細胞の樹立と毛包再生技術の確立
• 人工多能性幹細胞を用いた悪性黒色腫に対する養子免疫療法の確立

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